Compound Solutions' Dynamine gains GRAS status


The rapid-onset clean energy and focus ingredient is now recognised as safe for use in dietary supplements

Compound Solutions (CSI) has announced that Dynamine—a patented ingredient made of a purine alkaloid found in the kucha tea leaf (methylliberine)—has achieved self-affirmed GRAS (Generally Recognized As Safe) status.

Dynamine has been developed as rapid-onset clean energy and focus ingredient exclusively distributed by CSI globally. The GRAS status paves the way for the ingredient to disrupt the energy drink marketplace, CSI claims.

The GRAS status builds on six years of research and development, five safety studies and more than $600,000 in safety data.

“We’ve never seen an ingredient with this level of sensory experience—and safety profile—all in one package,” said Matt Titlow, Compound Solutions CEO.

“Dynamine will absolutely change the game in energy, gaming and biohacking formulas. Now that Dynamine is GRAS, the door is wide open for the largest brands in the world to give their consumers the best possible energy, mood and focus products without worrying about safety.”

We’ve never seen an ingredient with this level of sensory experience—and safety profile—all in one package

Dynamine’s safety is supported by toxicological and clinical scientific studies in humans without the occurrence of significant adverse events.**

Jacob Fishback, Brand Developer and Product Formulator for Lief Labs added: “When an energy ingredient like Dynamine achieves GRAS status, we can formulate a product with longevity behind it and we won't have to worry that it is going to hit the FDA’s chopping block at any given moment.”

Compound Solutions is a California-based company representing and distributing unique, patented nutraceutical ingredients for the sports nutrition, functional food and beverage and nutritional supplement markets.


**Stratton M, Holmes A, et al. A72. Effect of Dynamine™ With and Without TeaCrine® Over Four Weeks of Continuous Use on Cardiovascular Function, and Psychometric Parameters: A Pilot Study. Journal of the International Society of Sports Nutrition. 2018;15(256)

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** Timothy Murbach, Róbert Glávits, John Endres, et al. "A Toxicological Evaluation of Methylliberine (Dynamine™)," Journal of Toxicology, Vol .2019. Accepted for publication.