Folate and Pregnancy, MTHFR polymorphism

Gnosis has published a new News from Science issue focusing on Quatrefolic the innovActive folate and the implications of MTHFR polymorphism in pregnancy, continuing its dedication to education and awareness on the world of folate

Folate status in pregnancy is a critical factor in proper fetal development.

Since humans cannot synthesise folate and pregnant women do not consume adequate quantities of it through their diet, folate supplementation is required to prevent NTDs (neural tube defects) and is established by several Health Authorities (i.e. FDA, EFSA).

Folic acid is not biologically active and needs to be converted into the metabolically active 5-methyltetrahydrofolate (5-MTHF) through a multi-steps process where the enzyme methylenetetrahydrofolate reductase (MTHFR) has a key role.

Some individuals, due to their unique genetic patterns and expression, have polymorphic forms of this enzyme and do not produce adequate or effective MTHFR.

Quatrefolic is the structural analogue to the reduced and active form of folate so it completely bypasses the damaged MTHFR conversion step and delivers a finished folate the body can immediately use without any kind of metabolisation.

Click here to download the News from Science issue

Featured Companies

Gnosis by Lesaffre (more information, website)