The results have been published in the Journal of Stroke and Cerebrovascular Diseases and Current Neurovascular Research
Kemin Industries has announced the results of preclinical research on its dietary supplement for cognitive and physical benefits, Neumentix.
Researchers found Neumentix helped improve or restore cognitive and motor performance of mice following a mid-brain ischemic stroke. Animals treated with Neumentix before and after the procedure scored better in a sensory-motor functional assessment ('corner test') and presented less motor impairment than untreated animals.
Brain tissue analysis showed Neumentix protected neurons by reducing the expression of markers of oxidative stress (4-HNE, CML, 8-OHdG) and inflammation (Iba-1, MCP-1, TNF-a). The markers over express following a stroke and may worsen brain damage. In addition, the study demonstrated that Neumentix improved the integrity of the blood-brain barrier. The positive results for the Neumentix group in the study were statistically significant compared with the control group.
“The present study provides evidence of Neumentix’s anti-inflammatory and neuroprotective properties,” said Koji Abe, M.D., Ph.D., Professor and Chairman of Neurology at Okayama University Medical School in Japan and lead researcher for the study. “This research further illuminates the mechanisms by which Neumentix supports brain health and cognitive function.”
Neumentix contains a blend of more than 50 polyphenols. Extracted from a patented strain of spearmint, Neumentix contains high concentrations of rosmarinic acid as well as salvianolic, lithospermic and caftaric acids. These antioxidants protect brain and other cells against free radicals, which are unstable molecules produced naturally in the body as cells turn food into energy.
Previous clinical research showed Neumentix may improve working memory, the ability to concentrate and physical performance associated with agility and reaction time. It's Generally Recognized as Safe (GRAS) by the FDA and non-GMO Project Verified.
“This important new research provides further evidence of the antioxidant strength of Neumentix, which protects neurons and gets to the right areas of the brain to enhance the ability to focus and support short-term memory and physical agility,” said Kim Edwards, Global Product Manager, Kemin Human Nutrition and Health. “These multiple health benefits can differentiate products and enable a wide range of science-based marketing claims.”