Indena is set to unveil a new R&D development lab for Highly Potent APIs at DCAT2023.
“Driven by the increased number of running projects, a major expansion of the R&D building has been planned to respond to customers’ demand," said Bernard Vianes, Global Director CDMO Indena. "The expansion program includes the construction of a brand new R&D development laboratory of 400 sqm equipped with 12 fumehoods, 2 walk-in fumehoods, 1 laminar flow fumehood, 2 gloveboxes that will be able to host 15 R&D scientists. The project has been authorised in December 2022 and the new laboratory will be up and running by end 2023”.
The new multipurpose GMP plant, the HPAPI kilolabs and a PSD2 spray dryer from organic solvents are only examples of the latest investments carried out in the last few years and underlines that the CDMO business area is a top priorities for Indena’s strategic development.
“What Indena has learned in this experience of working with nature has taught the company to manage complex molecules of any type, from both the analytical and the production perspectives. Nowadays Indena manufactures 12 commercial HPAPIs from various origins: fully synthetic, semi-synthetic and fermentation molecules," added Pietro Allegrini, R&D Director Indena. "Each substance within Indena is assigned an Occupational Exposure Level and allocated to the proper production line according to the required handling and containment rules. At its Settala facility, Indena can handle HPAPI with an OEL down to 20 ng/m3”.
Nowadays Indena manufactures 12 commercial HPAPIs from various origins: fully synthetic, semi-synthetic and fermentation molecules
With the aim of providing customers with an increasing range of services the company has indeed been investing in the implementation of cutting-edge technologies; the plans for the future are to continue investing by further expanding the capacity for both NCEs and consolidated APIs.
For 2023 and 2024, Indena has planned the expansion of the existing GMP plant, the installation of pilot scale hydrogenator and the expansion of the R&D lab for highly potent compounds.
As well as custom services excellence, Indena pursuits a strong commitment to sustainability. Among its actions taken in such field is the smart use of energy in its plants.
At its Settala site, near Milan in Italy, where Indena’s CDMO activities are implemented, a natural gas cogeneration plant, operational since 2016, produces 16.6 gigawatt-hours per year, both as electric and thermal energy, and enables a reduction of 1.699 tons Equivalent Petrol (PET), that means a reduction of 2,500 tons of CO2 emissions per year.
All the actions taken in favour of sustainability also enable Indena to be fully reliable in terms of business continuity, and therefore to be a solid partner for all its clients.