DSM joins scientific community to highlight beneficial effects of vitamin E on fatty liver disease

28-May-2014

Dr Arun Sanyal at Virginia Commonwealth University has found Vitamin E prevents progression of this disease

DSM is working with the scientific community as part of efforts to further its understanding of the ways in which vitamin E can support human health. These cover a variety of areas of research, including the role of vitamin E supplementation in limiting the negative health implications of fatty liver disease, the use of vitamin E in model systems to prevent the sequelae of stroke and the actions of vitamin E in facilitating membrane repair.

The scientific experts include Arun Sanyal at the Virginia Commonwealth University, who has published studies on the efficacy of vitamin E to prevent the progression of non-alcoholic fatty liver disease. The results of several human studies have demonstrated the benefit of vitamin E compared with placebo. Vitamin E was found to be effective in reducing the disease activity of non-alcoholic fatty liver disease, was safe in the applied dose and did not lead to side effects such as weight gain.

\'This is a significant development, as obesity-related conditions such as non-alcoholic fatty liver disease become key public health concerns on a global scale,\' said Sanyal. \'The results are clear evidence of the benefits that vitamin E supplementation can provide when there are no approved pharmacological treatments available. We [now] need to address the potential concerns related to the long term safety of vitamin E, dose responses for non-alcoholic fatty liver disease and whether the data from previous trials can be generalised.\'

\'Vitamin E is vital to supporting human health, yet it is estimated that more than 90% of the population in the US does not meet the dietary intake recommendations for vitamin E,\' added Professor Manfred Eggersdorfer, Senior Vice President, Nutrition Science & Advocacy at DSM and Professor for Healthy Ageing at University Groningen.

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\'While the micronutrient is not currently high on the agenda of scientists and funding organisations, there is an urgent requirement for additional research to understand the benefits of vitamin E span beyond its well-known function as a fat soluble antioxidant. DSM is working to advance scientific understanding and we regularly attend events that provide an important forum for sharing exciting new discoveries.\'

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