In the evolving world of dietary supplements, the demand for diverse, convenient, and high-performance products has never been greater. Consumers are increasingly seeking alternatives to traditional tablets and capsules, with formats like beverages, chews, and infused snacks gaining popularity. To meet this shift, Gnosis has unveiled Quatrefolic® PRO, an innovative folate ingredient designed to elevate supplement formulations while offering superior stability, solubility, and bioavailability.
Quatrefolic® PRO builds on Gnosis's commitment to delivering cutting-edge solutions that not only enhance the consumer experience but also streamline manufacturing processes. This new form of active folate brings multiple benefits to both formulators and manufacturers, making it easier than ever to create products that are both effective and efficient.
What sets Quatrefolic® PRO apart?
Quatrefolic® PRO stands out in the crowded supplement space for its advanced characteristics, designed to meet the demands of modern formulation needs. The ingredient boasts high stability, improved smoothness and flowability, as well as exceptional solubility, making it ideal for a wide range of product forms, from tablets to liquid suspensions and oral sprays.
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Consistency in dosage
One of the primary challenges in supplement production is ensuring each unit contains a precise amount of the active ingredient. With Quatrefolic® PRO, manufacturers can achieve consistent dosing in every product. By eliminating variability in powder density, Quatrefolic® PRO ensures uniformity, providing both formulators and consumers with peace of mind that each product contains the correct amount of active folate. -
Optimal formulation flexibility
The superior flowability of Quatrefolic® PRO enables smoother tablet compression and easier filling into capsules, thereby enhancing the manufacturing process. This flexibility makes it ideal for companies looking to create more innovative and diverse supplement formats — whether traditional tablets or more complex, multi-phase products. -
Enhanced quality control
Quatrefolic® PRO offers a level of precision that improves overall product consistency. Minimizing fluctuations in bulk density and particle size helps ensure the final product performs at its best. This high standard of quality control means manufacturers can deliver reliable, high-quality supplements that consumers can trust. -
Improved handling properties
By understanding the tapped density and optimizing compaction processes, Quatrefolic® PRO reduces waste during tablet pressing and capsule filling. This results in a more efficient use of materials, lowers production costs, and enhances sustainability, all while ensuring the highest quality in the final product.

A new era of supplement innovation
Quatrefolic® PRO is the latest in Gnosis's lineup of advanced folate ingredients, joining the original Quatrefolic® and Quatrefolic® Fine Powder. With its superior properties, Quatrefolic® PRO makes it easier for manufacturers to create innovative supplements that meet the diverse and growing needs of today’s consumers. Its stability, solubility, and ease of use in various formulations mark a new chapter in the development of effective, high-quality dietary supplements.
By providing reliable, cost-effective, and versatile solutions, Gnosis continues to lead the way in supplement innovation. Quatrefolic® PRO exemplifies the company’s commitment to meeting the challenges of modern product development and helping manufacturers deliver the best possible products to the market.