The world of tablet formulation and compression is complex. Not only do product developers have to consider dissolution properties, there are also issues to address such as shelf-life, stability and exposure to environmental hazards, such as oxygen, light, humidity, high or low temperatures. Also due to the high number as well as load of active ingredients in the formulation, the production of nutraceutical tablets can be difficult. In addition, herbal extracts, which are increasingly getting popular, are often only poorly compactable and tabletting turns out to be a challenge. Thus, formulators must select appropriate tablet processing aids — excipients — to optimise the compressibility and disintegration of the compound.
Omya’s new mineral solutions help facilitate this process. With Omyanutra® 300 DC and Omyanutra® 300 Flash, manufacturers can create hard tablets at low compression forces. They allow for better flowing and direct compressible formulations with enhanced compactability compared to other existing direct compressible excipients such as lactose and microcrystalline cellulose. In addition, the minerals provide fast disintegration thanks to their particles’ porous structure. This porosity also enables the safe carrying and release of active ingredients. As it contains a superdisintegrant, Omyanutra® 300 Flash is ideally suited to tablet manufacturers looking for an all-in-one solution. It provides fast disintegration in orally and fast dissolving tablets (ODTs/FDTs) regardless of the hardness of the solid dosage form.
These new excipients are just two examples of the many solutions Omya offers for manufacturers who are looking for natural, effective and easy to process ingredients to speed up product developments.
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