Gnosis by Lesaffre believes that health is more than just the absence of illness; it’s about thriving in every moment, embracing vitality and living purposefully.
In a world where people live longer, the true challenge lies in ensuring that those extra years are filled with energy, strength and well‑being.
At Vitafoods, Gnosis is excited to showcase how its innovative solutions address this challenge head-on by bridging natural processes with the cutting-edge advancements of modern science.
With decades of expertise in biotransformation and fermentation, Gnosis is leading the charge by redefining human health. Focused squarely on proactive health solutions beyond traditional treatments, the company aims to pre-empt illness before it starts.
Working with nutritional yeasts, biotics and active ingredients, Gnosis is pioneering products that support whole-body wellness and nurture the mind.
This approach is rooted in sustainability by using nature’s processes to create solutions that are as good for the planet as they are for people.
Sustainability and safety for joint health
The nutraceutical industry must constantly innovate to meet growing consumer demand for safety, sustainability and efficacy.
Chondroitin sulphate, a key ingredient in joint health products, has traditionally been sourced from animal cartilage, leading to significant concerns about quality inconsistencies, adulteration and potential safety risks, including contamination with transmissible agents.
Additionally, the reliance on animal-derived sources raises ethical and environmental challenges. Gnosis, the Joint Health Sponsor for Vitafoods Europe, transforms this market with MyCondro, a category disrupting, fermentation-derived chondroitin sulphate that sets new industry standards.
By eliminating the variability and risks associated with animal sources, MyCondro offers an exceptionally pure, highly consistent ingredient that’s free from contaminants.
Its fermentation-based production ensures a chondroitin sulphate content exceeding 95%, surpassing the USP standard and guaranteeing superior quality. Beyond purity, MyCondro demonstrates a breakthrough in efficacy.
It delivers scientifically validated benefits for joint health with 45% greater bioavailability than animal-derived chondroitin and proven effectiveness at a lower dosage (600 versus 800–1200 mg/day).
Clinical studies confirm significant improvements in knee function, pain reduction and inflammation markers, making it a superior alternative for consumers and brand owners.
As the industry shifts toward more sustainable and multifunctional ingredients, MyCondro is paving the way for expanded applications beyond joint health, including digestive support, metabolic health and inflammation management.
The power of probiotic yeast
Functional digestive disorders can affect anyone, anywhere (a 2023 study showed that two-thirds of American adults experience recurrent digestive symptoms) and greatly impact their quality of life.
Scientific advancements and a growing awareness of the gut microbiome’s role have shifted perceptions, highlighting its influence on immunity, mental health and the avoidance of chronic disease.
As a result, digestive health has become a key focus in wellness and proactive healthcare.
Gnosis understands this better than most as it is the only company to provide several complementary strains of Saccharomyces cerevisiae (S. cerevisiae) probiotic yeasts.
With strains clinically validated to provide overwhelmingly significant targeted benefits, the company’s biotics offering is unique in a market overrun by probiotic bacteria.
These patented yeast strains come with 170 years of fermentation expertise and are perfect when it comes to supporting gut health during antibiotic therapy as they are not affected.
Further, they offer high stability, no colonisation effect, resistance to gastric acid and bile salts, and require no protective encapsulation. ibSium is a reference probiotic yeast developed by Gnosis (patented and registered under S. cerevisiae CNCM I-3856).
Thanks to four double-blind placebo-controlled clinical studies and a meta-analysis, it has been demonstrated that ibSium can relieve occasional abdominal pain and improve the quality of life of people suffering from digestive discomfort.
This includes alleviating abdominal pain, bloating, constipation and diarrhoea, all leading to enhanced quality of life.
Gnosis also offers Lynside S. cerevisiae var. boulardii — a proprietary strain of Lesaffre’s registered as CNCM I-3799. It is the most documented probiotic yeast with more than 65 years of clinical research supporting the gut barrier defence system.
S. boulardii has been clinically proven to reduce diarrhoea in adults and children and help to restore a balanced microbiota.
Finally, Gnosis offers Quatreflora, a specialised probiotic yeast (S. cerevisiae CNCM I-3856) that benefits women who experience yeast infections caused by C. albicans.
It offers distinctive benefits compared with the probiotic bacteria consumed to mitigate yeast infections.
Although probiotic strains are subject to neutralisation, probiotic yeast has been shown to migrate intact from the intestine, surviving the stomach, and into the vagina where it can go to work against Candida species.
This was proven in a randomised, double-blind, placebo-controlled clinical trial evaluating the recovery of orally consumed S. cerevisiae CNCM I-3856.
Furthermore, oral administration offers better compliance, the pet peeve when women start proactive therapy.
Formulation freedom for women’s health
At the forefront of Gnosis’ efforts to enhance women’s health is Quatrefolic. This most bioavailable form of folate, 5-MTHF in a glucosamine salt, provides superior stability and bioavailability to ensure that the body can utilise folate efficiently and quickly.
Folate (vitamin B9) is necessary for numerous body processes, including DNA synthesis and repair, proper cellular division and amino acid metabolism.
Consumers of all ages can benefit from adequate folate intake as it supports fertility, pregnancy, menopause and both heart and cognitive health. Gnosis developed Quatrefolic Fine Powder specifically for use in oily liquid suspensions, oral sprays and complex softgels.
Most existing liquid folate formulations are primarily aqueous-based, often leading to stability issues that limit their broader application.
To overcome this, Gnosis has invented and patented a stable oily-liquid formulation of folates. The key innovation lies in suspending the active Quatrefolic ingredient in a blend of medium-chain triglyceride oil and stearin.
This proprietary formulation process eliminates the risk of sedimentation, enhances the suspension capacity in oil and improves the folate’s overall chemical and physical stability.
Further, extensive testing has demonstrated no drop in potency or colour changes.
The standard bearer of clinical evidence
Everything the industry understands about the importance of vitamin K2 as MK-7 (menaquinone-7) begins with MenaQ7.
The actual source material for more than 22 published human clinical trials, MenaQ7 is the most clinically proven K2 as MK-7 for bone health in children and adults and cardiovascular health in adults.
Yet, Gnosis is not stopping there. Assembling some of the most esteemed researchers for the Vitamin K2 Scientific Advisory Committee, the company continues to explore this amazing vitamin’s potential.
In addition to adding to the evidence showing heart and bone support, it is deeply invested in trials to confirm benefits beyond, including a study focused on K2’s potential to reduce the frequency of migraine attacks.
Beyond rock-solid clinical validation, MenaQ7 offers other core advantages, including being naturally produced by fermentation in Gnosis’ European facility and incredible portfolio diversity, including the award-winning MenaQ7 Matrix protective technology, which ensures stability in even the most complex formulations.
Conclusion
As Gnosis continues to innovate at the intersection of microbiology and science, its goal is clear: to raise the standard of human health for future generations.
It’s not just providing products but creating a movement toward a healthier, more vibrant future.