Strong data backing across gut, immune and barrier health
At the core of NutriLeads’ showcase is fresh human clinical data. In a new randomised, double-blind, placebo-controlled trial published in Microorganisms, healthy adult participants were supplemented with Benicaros (cRG-I, carrot-derived rhamnogalacturonan-I) for four weeks. Results included:
- Robust prebiotic effect: Significant increases in Bifidobacteria levels were observed, with the peak at week three.
- Immune training support: The data confirm earlier findings that Benicaros primes innate immune cells, now also showing likely involvement of dendritic cells - key immune “scouts”.
- Microbiota balance and gut function: Even in subjects already on fibre-rich diets, Benicaros further improved microbiota balance and stool consistency.
- Barrier protection in vitro: Complementary laboratory assays show that Benicaros and its fermentation metabolites (notably short-chain fatty acids) help safeguard gut barrier integrity under stress or inflammatory conditions.
Importantly, the supplement was well tolerated, with excellent compliance - reinforcing its suitability for consumer formulations.
These findings form the foundation of a new white paper on gut health, barrier function and immune modulation via Benicaros, which NutriLeads will debut at SupplySide Global.
Demonstrating real-world application and innovation
At SupplySide Global, NutriLeads is not just presenting science - it is also showing how Benicaros can be integrated practically into product pipelines.
- Benicaros F&B version: Tailored for functional food and beverage formats, this variant offers the same validated benefits in a one-gram daily dose, designed to support flexible formulation without compromising efficacy, sensory quality, shelf-life stability or clean label expectations.
- Application demos and sampling: Attendees at booth #6173 can sample Benicaros gummies, observe formulation prototypes and engage with the team.
Sue McKay, PhD (Nutrition & Health Manager, NutriLeads), emphasises:
Benicaros continues to stand out because of its robust science demonstrating consistent benefits for all gut ecosystems and for immune health
Why supplement innovators should care
In a crowded marketplace, differentiation is key. Benicaros offers several strategic advantages:
- Low effective dose - Its potency allows for a broad range of formats thanks to its daily serving size, which can be as low as 300 mg.
- Clinically validated, multifunctional impact - Supports gut microbiome modulation and immune training, with in vitro studies also showing benefits for gut barrier health.]
- Performance across diverse gut ecologies - Delivers consistent benefits in varying gut microbiome ecosystems, even in high-fibre diets.
- Clean label, plant-based origin and strong tolerability - Derived from upcycled carrot fibre, non-GMO, and well tolerated in human trials.
- Formulation flexibility - The F&B variant expands options for brands seeking consumer-friendly formats beyond capsules and powders.
Visit booth #6173 and get the white paper
For supplement manufacturers seeking science-driven differentiation, NutriLeads invites you to meet its team at booth #6173 at SupplySide Global 2025. Get your copy of the Benicaros white paper, explore formulation paths tailored to your needs, and discuss partnership or sampling options.
Not attending the show? You can still access the full white paper afterwards - just fill in the contact form and type ‘white paper’ in the message field. The NutriLeads team will ensure you receive your copy following SupplySide Global.
Don’t miss the chance to align your next-generation supplement formulations with clinical innovation, precision prebiotic science and proven multifunctional performance.
