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The nutricosmetics market is undergoing a fundamental transformation. Supplement consumers are moving away from reactive correction towards proactive, holistic cellular health. In parallel, modern research now views skin ageing as a multifactorial biological process driven by the 14 Hallmarks of Ageing (Carlos Lopez-Otin et al.).
Among these hallmarks, inflamm’aging, a chronic, low-grade inflammatory state, acts as a primary driver of structural skin decline. Environmental stressors generate reactive oxygen species (ROS), activating the NF-κB transcription factor. This molecular switch triggers a continuous loop of pro-inflammatory cytokines, accelerating matrix degradation and skin ageing.
To mitigate this destructive cascade at the root, Seppic developed SepiblissTM, a 100% natural, eco-extracted coriander seed oil sourced and produced in France. Rich in rare petroselinic acid (omega-12), linoleic acid (omega-6), and antioxidant phytosterols and tocols, SepiblissTM acts simultaneously on oxidative stress and cellular inflammation.
The efficacy of SepiblissTM is validated by 3 gold-standard Randomized Controlled Trials (RCTs) conducted on 239 women:
- Oxidative defence: Reduces Malondialdehyde (MDA), a marker of lipid peroxidation by 32% within 4 hours post-UV exposure.
- Inflammatory control: Decreases major inflammatory marker TNF-α by 19% and inhibits NF-κB, the cellular switch of inflammation, by 38%.
- Clinical anti-ageing efficacy: Delivers visible improvements as early as 2 weeks, reducing wrinkle depth by 9% and increasing skin firmness by 7%.
- Barrier reinforcement: Decreases transepidermal water loss (TEWL) by 10% after 1 month of supplementation.
Available in both solvent-free oil and spray-dried powder grades, SepiblissTM provides high formulation versatility for capsules, tablets, gummies, softgels, and functional drinks.
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