Pendulum launches flavourless Gut Fuel prebiotic blend to support microbiome and GLP-1 signalling

Published: 26-Mar-2026

US gut health company Pendulum Therapeutics has introduced Gut Fuel, a doctor-formulated prebiotic fibre and polyphenol powder combining resistant potato starch, baobab, acacia, oat beta-glucan and grape seed extract to support the microbiome, metabolic function and natural GLP-1 pathways

Pendulum Therapeutics has announced the launch of Gut Fuel, its flavourless prebiotic fibre and polyphenol blend.

The powder, which is launching online, can be added seamlessly to foods and beverages to "fuel the gut, digestion and health from the inside out."

The doctor-formulated blend of plant-based fibres and polyphenols is purported to aid digestion and improve regularity, as well as to help to feed healthy bacteria in the gut microbiome, which Pendulum claims "supports the body's natural GLP-1 signalling pathways."

Ingredients such as resistant potato starch, baobab, acacia, oat beta-glucan and grape seed extract provide the six grams of fibre per serving, helping to maintain healthy blood sugar levels and metabolic function, enhance satiety, improve digestion and boost keystone gut bacteria.

Gut Fuel is the latest addition to Pendulum's consumer-friendly, results-driven line of pre- and probiotics—crafted to increase antioxidants, support rich fibre diversity and amplify the performance of Pendulum's other products.

"Just as we need to feed our bodies, we need to feed the healthy bacteria in our gut microbiome," said Pendulum co-founder and CEO Dr Colleen Cutcliffe.

The resistant starches, diverse fibres and polyphenol antioxidants in Pendulum Gut Fuel nourish beneficial gut bacteria—and because it blends seamlessly into everyday foods, it turns virtually any meal into a superfood that closes the fibre gap and supports the microbiome.

95% of American adults and children don't consume the recommended amounts of dietary fibre (American Journal of Lifestyle Medicine, 2016) and many children get only 30-50% of what they need.

At the same time, polyphenols—powerful antioxidants with anti-inflammatory benefits—are often under-consumed. Bridging this nutritional gap is critical for gut health. Gut Fuel makes it easy to add both prebiotic fibre and polyphenols, especially for those with sensitive guts or on a low-FODMAP diet.

"The gut microbiome is the underpinning of so many systems in the body," said Dr Adam Perlman, Chief Medical Officer of Pendulum Therapeutics.

When your gut is thriving, your metabolism, immunity, sleep, mood and even longevity are all improved. This is not just about digestion any more, though that will also improve.

Pendulum stated that Gut Fuel can be easily incorporated into any dish or beverage without altering its flavour.

It is available in two options: a 30-serving pouch or a package containing 15 individual serving sticks. Additionally, it can be purchased using HSA or FSA funds.

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